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NHGRI

Knockout Mice Fact Sheet

sheet  mice  knockout  nhgri 

A knockout mouse is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by replacing it or disrupting it with an artificial piece of DNA.

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NHGRI

FAQ About Newborn Screening

screening  newborn  FAQ  nhgri 

Newborn screening tests use a dried blood sample collected during the first week after birth to measure the presence of disease biomarkers (a measurable substance or characteristic that is indicative of a disease).

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NHGRI

Polymerase Chain Reaction (PCR)

polymerase  chain  reaction  PCR  nhgri 

Sometimes called "molecular photocopying," the polymerase chain reaction (PCR) is a fast and inexpensive technique used to "amplify" - copy - small segments of DNA. Because significant amounts of a sample of DNA are necessary for molecular and genetic analyses, studies of isolated pieces of DNA are nearly impossible without PCR amplification.

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NHGRI

Deoxyribonucleic Acid (DNA) Fact Sheet

sheet  acid  DNA  deoxyribonucleic  nhgri 

Deoxyribonucleic acid (DNA) is a molecule which contains the biological instructions that make each species unique. DNA, along with the instructions it contains, is passed from adult organisms to their offspring during reproduction.

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NHGRI

Genetic Information Nondiscrimination Act of 2008

information  act  genetic  2008  nondiscrimination  nhgri 

Genetic discrimination occurs if people are treated unfairly because of differences in their DNA that increase their chances of getting a certain disease. For example, a health insurer might refuse to give coverage to a woman who has a DNA difference that raises her odds of getting breast cancer. Employers also could use DNA information to decide whether to hire or fire workers.

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