Preventing Chronic Disease | Comparison of Fecal Occult Blood Tests for Colorectal Cancer Screening in an Alaska Native Population With High Prevalence of Helicobacter pylori Infection, 2008 to 2012 - CDC

Alaska Native colorectal cancer (CRC) incidence and mortality rates are the highest of any ethnic/racial group in the United States. CRC screening using guaiac-based fecal occult blood tests (gFOBT) are not recommended for Alaska Native people because of false-positive results associated with a high prevalence of Helicobacter pylori-associated hemorrhagic gastritis. This study evaluated whether the newer immunochemical FOBT (iFOBT) resulted in a lower false-positive rate and higher specificity for detecting advanced colorectal neoplasia than gFOBT in a population with elevated prevalence of H. pylori infection.


Media Type: Html
  • SourceUrl: http://www.cdc.gov/pcd/issues/2014/13_0281.htm
  • Syndication ID: 10667
  • Language: English
  • Source: Centers for Disease Control and Prevention (CDC)
  • Date Syndication Captured: Monday, May 23, 2016 at 10:40 PM
  • Date Syndication Updated: Monday, May 23, 2016 at 10:40 PM

Tags

General: CDC Helicobacter pylori Colonoscopy alaska native sensitivity specificity Preventing Chronic Disease PCD Colorectal Neoplasms immunochemical occult blood

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