In this Director's Briefing video, CDC Director Dr. Tom Frieden talks about drug-resistant bacteria called CRE. These bacteria pose a triple-threat: especially deadly, outsmarting our best antibiotics, and easily transfer their resistance to other germs. Patients are left with extremely limited, and in some cases, no treatment options. This Vital Signs (www.cdc.gov/vitalsigns) reports that CRE are spreading in U.S. medical facilities. More normal bacteria are becoming highly-resistant CRE. These bacteria could be the beginning of the end of antibiotics, and the entire healthcare community must act now to stop them. Comments on this video are allowed in accordance with our comment policy: http://www.cdc.gov/SocialMedia/Tools/CommentPolicy.html This video can also be viewed at http://streaming.cdc.gov/vod.php?id=5fac59254239fa5599f8fd0fd48230ed20130304094025116