Previous reports have described cases of influenza A (H3N2) variant (H3N2v) virus* infection with the influenza A (H1N1)pdm09 M gene detected in the United States during July 2011–July 2012 (1–3). This report provides 1) an update on the number of reported cases of H3N2v infections from July 12 to August 9, 2012, in the United States, 2) an updated results interpretation for the CDC Flu Real-Time Reverse Transcription Polymerase Chain Reaction (rRT-PCR) Dx Panel for A(H3N2)v for public health laboratories, and 3) an evaluation of rapid influenza diagnostic tests for the detection of H3N2v viruses.