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Researchers, clinicians, and patients across the country will need to share their collective data and knowledge to enable the development of new technologies and reduce the burden of cancer. This Cancer Moonshot initiative empowers and encourages such collaboration.

This Moonshot initiative aims to develop effective cancer prevention and early detection approaches for those at high risk for inherited cancer syndromes and implement appropriate clinical management.

This Cancer Moonshot initiative aims to establish a pediatric cancer immunotherapy network to discover and characterize new targets for immunotherapies and ultimately develop new, effective immunotherapy treatments for children and adolescents with cancer.

This initiative aims to develop, test, and adopt proven cancer prevention and early detection approaches to reduce cancer risk and cancer health disparities in all populations.

This Cancer Moonshot initiative will engage patients to contribute their tumor profile data to expand knowledge about what therapies work, in whom, and in which types of cancer. A patient’s genomic data may guide treatment decisions.

The development of cancer technologies to characterize tumors and test therapies can transform cancer research and clinical care.

Fusion oncoproteins can lead to the development of childhood cancers. This Cancer Moonshot initiative aims to improve our understanding of these proteins and develop inhibitors that target them.

Cancer Moonshot initiative to develop a better system for monitoring and managing patient-reported side effects, in an effort to minimize debilitating side effects and reduce cancer costs related to poorly controlled symptoms.

Tumor samples and other biospecimens can be analyzed retrospectively to develop hypotheses about which tumor features can help predict clinical benefit. Ideally, this information can be used to improve treatment and outcomes for cancer patients.

Cancer cells can develop resistance to drugs that were previously effective. This Cancer Moonshot initiative aims to increase understanding of how this resistance develops, and to use biomarkers to predict who will develop it, and ways to counteract it to improve patient care and survival.