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Many women develop irregular menstrual cycles which may make it difficult to become pregnant and increase the risk of osteoporosis.

According to the Centers for Disease Control and Prevention, cigarette smoking causes more than 480,000 deaths each year in the United States, which translates to causing nearly one of every five deaths.

The Environmental Polymorphisms Registry (EPR) is a long-term initiative to collect approximately 20,000 DNA samples from individuals.

The gene p53 suppresses cancer and inflammation in the body, and NIEHS investigators speculate that changes in p53 lead to changes in inflammation and the ability to repair DNA damage.

Researchers are interested in developing a registry protocol to obtain biologic and environmental samples anonymously from adult volunteers for use in laboratory tests and studies.

Asthma patients seem to be more prone to viral infections, and NIEHS scientists believe that the cells that line these patients' airways, cause this result by overproducing TGF-beta1, a protein that promotes viral growth.

NIEHS researchers theorize that changes in the surface proteins of cells called receptors may predispose people to diseases, such as heart disease, arthritis, and diabetes.

NIEHS Studies - Open for Recruitment

Innate immunity is the process by which white blood cells and other parts of the immune system sense and respond to potential infections by causing an inflammation.

The Innate Immunity Signal Transduction in Human Leukocytes is a research study to determine the response of immune cells from the bloodstream.